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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRWD1
All Species:
22.42
Human Site:
S418
Identified Species:
49.33
UniProt:
Q9NSI6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSI6
NP_061836.2
2320
262920
S418
T
R
I
S
G
D
L
S
S
E
E
E
R
F
M
Chimpanzee
Pan troglodytes
XP_001170924
2320
262999
S418
T
R
I
S
G
D
L
S
S
E
E
E
R
F
M
Rhesus Macaque
Macaca mulatta
XP_001108655
2320
262912
S418
T
R
I
S
G
D
L
S
S
E
E
E
R
F
M
Dog
Lupus familis
XP_544889
2401
270094
S493
T
R
V
S
G
D
L
S
L
E
E
E
R
F
M
Cat
Felis silvestris
Mouse
Mus musculus
Q921C3
2304
259007
S418
A
R
I
S
G
D
T
S
S
E
E
E
R
F
M
Rat
Rattus norvegicus
XP_001054667
1799
202807
Y13
T
Q
I
E
A
E
L
Y
Y
L
I
A
R
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510724
2599
293992
S418
T
R
L
S
D
D
Q
S
E
E
E
K
F
M
K
Chicken
Gallus gallus
XP_416730
2299
260504
C421
D
R
L
P
G
D
M
C
S
D
E
D
K
F
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920441
2191
247687
W399
R
D
G
T
A
R
I
W
R
L
H
Q
R
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395863
1676
190205
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201169
1837
210307
I51
K
N
D
H
L
L
K
I
V
G
R
I
G
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
85.7
N.A.
78.7
44.7
N.A.
65.6
61.8
N.A.
44.7
N.A.
N.A.
34.9
N.A.
27.3
Protein Similarity:
100
99.7
98.7
89.7
N.A.
86.1
57.7
N.A.
74.3
73.4
N.A.
61.4
N.A.
N.A.
49.4
N.A.
42.3
P-Site Identity:
100
100
100
86.6
N.A.
86.6
33.3
N.A.
46.6
46.6
N.A.
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
53.3
N.A.
60
80
N.A.
26.6
N.A.
N.A.
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
10
64
0
0
0
10
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
0
10
55
64
46
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
64
0
% F
% Gly:
0
0
10
0
55
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
0
19
0
% H
% Ile:
0
0
46
0
0
0
10
10
0
0
10
10
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
10
10
0
10
% K
% Leu:
0
0
19
0
10
10
46
0
10
19
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
55
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
10
% Q
% Arg:
10
64
0
0
0
10
0
0
10
0
10
0
64
0
0
% R
% Ser:
0
0
0
55
0
0
0
55
46
0
0
0
0
0
0
% S
% Thr:
55
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _